On March 31, 2008 the Diamondbacks would visit the Cincinnati Reds at Great American Ballpark in Cincinnati OH.
For the third consecutive season right-handed pitcher Brandon Webb would take the mound for the Arizona Diamondbacks.
The Opening Day line-up featured only two changes from the previous season.
Mark Reynolds was the new third baseman. First overall draft pick Justin Upton made his first Opening Day roster and line-up playing right field moving Eric Byrnes to left field.
For the fifth time in franchise history the Diamondbacks won their season opener. The final score Diamondbacks 4 - Reds 2 in front of 42,498.
Select a season to see who was in the starting line-up for the team that year: